estranged

UK: ɪˈstreɪndʒd | US: ɪˈstreɪndʒd

Definition
  1. adj. (of a person) no longer close or affectionate to someone; alienated

  2. vt. (past tense) caused someone to feel isolated or alienated

Structure
e <away, from Latin "ex">strange <foreign, from Latin "extraneus">
Etymology

The word "estranged" originates from the Latin "extraneus" (meaning "foreign" or "external"), which evolved into Old French "estrangier" (to treat as a stranger). The prefix "e-" (from Latin "ex") intensifies the sense of separation. Over time, "estrange" came to mean "to alienate" or "to distance emotionally," reflecting the idea of making someone feel like a stranger.

Examples
  1. After the argument, they became estranged for years.

  2. His harsh words estranged him from his family.

  3. She felt estranged in a room full of strangers.

  4. The political scandal estranged many of his supporters.

  5. Time and distance had estranged the once-close friends.