substance
UK: ˈsʌbstəns | US: ˈsʌbstəns
n. 1. A particular kind of matter with uniform properties.
n. 2. The real physical material of which something is made.
n. 3. The most important or essential part of something; essence.
Derived from Latin substantia ("being, essence"), from substare ("to stand under, exist"), combining sub- (under) and stare (to stand). The term originally referred to the underlying reality or essence beneath appearances, later evolving to denote physical matter or core importance in English.
Water is a substance essential for life.
The scientist analyzed the chemical substance in the lab.
His argument lacked substance and was easily dismissed.
The artist used unconventional substances in her sculpture.
The treaty addressed the substance of the dispute rather than superficial issues.